Medicinal Chemistry & Drug Discovery
Medicinal Chemistry & Drug Discovery
Synthesis of nitrogen heterocycles
Novel pyrazole derivatives were discovered in our lab and found to be good antimicrobial agents against different drug-resistant bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and Acinetobacter baumannii.
We have discovered efficient methodologies to synthesize thiazole-fused natural products and drugs. These thiazoles are very potent against melanoma in both in vitro and in vivo studies. Thiazole-fused nootkatones are antibacterial agents.
Computational Chemistry
Ethisterone
Molecular Docking